In AXIGEN Mail Server, you can activate Antivirus / Antispam filters by enabling them from 'AntiVirus and AntiSpam' context, and Message rules by adding and enabling them in the 'Incoming Message Rules' list, available in the 'Security & Filtering' menu in WebAdmin.

Filter Priority

Priorities between enabled Antivirus / Antispam filters or Message rules can be changed using the the up and down arrows under the Priority section from the same context that these can be Enabled/Disabled.

Activation Inheritance

All filters activated at server level, will automatically be applied at all filtering levels, according to their respective priority levels.

The same is true for domain level filters, which can be activated at account / mail list level.
Filters activated at domain level, are applied to all accounts belonging to the respective domain. Filters activated only at account level, will only be applied to that specific account.

For information on how to activate filters using WebAdmin see the following pages:
Managing Message Filters
Domain Filter Configuration
Account Filter Configuration
List Filter Configuration